Roleplayed this virtually, to great effect once with a good fun partner.
Same basic concept as mentioned above where it removed all inhibitions in men who became aggressive and predatory.
After a bite or infection through bodily fluids, the victim would initially slip into unconsciousness, effectively playing possum for many hours which both slowed the progression of the disease by reducing the R number and stopping the violence from being excessively fatal.
Women were not as aggressive in general, tended to hide once infected given the overwhelming and persistent pursuit of men.
My companion turned out to be immune so didn't succumb to the comatose phase and we had great fun with her trying to get home to her family, encountering characters from her real life (store owner, postman, husbands co-worker) along the way.
It was great to use the shock of collapse, the fear of being hunted and the confusion of seemingly being the only sane person left. The chase.
It took her a while to figure out that playing possum* when attacked was her only defense as she wasn't prepared to hurt or kill what she only saw as victims, quickly and often getting ganged once caught.
*As she quipped OOC, "It feels like my marriage"
I tried to avoid the mindless hordes of strangers (
Walking Dead/World War Z) and went for the
Invasion of the Body Snatchers/The Thing vibe.
One avenue I'd explore more nowadays, would be body horror where the disease caused interesting physical mutations and behaviors.
Possibly as an aliens adaptive cuckoo invasion strategy (The Midwich Cuckoos) where every infected female became pregnant with a hybrid drone offspring hijacking the maternal insrtincet.
When the initial infection burns out and society tries to rebuild in the aftermath.
Much like
In the Flesh (or arguably more recent events) where no-one can be held to account for heinous crimes but victims can't forget or forgive.
Anyway that's my two pence worth
